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HP D300 Digital Dispenser - Overview

Fast and accurate determination of a candidate compound’s IC50 provides drug discovery biologists with valuable information for the development of new pharmaceuticals, yet traditional techniques are both time­ consuming and laborious, with no standardization across the industry. The HP D300 Digital Dispenser offers a simple method for streamlining your workflow, offering picoliter to microliter non-contact dispensing of small molecules in DMSO directly into your assay plate. Using HP’s Direct Digital Dispensing technology, this convenient benchtop solution requires almost no set up time, and single use T8 Dispenseheads virtually eliminate the risk of cross­contamination. It allows rapid delivery of any dose to any well, saving time, minimizing waste of valuable compounds and accelerating drug discovery.

HP D300 unique features
Time Savings   Flexible plate maps		Drug-drug interaction studies   Digital Dispensing

[x]  Time Savings HP D300 will streamline the drug titration workflow, saving time and money. The HP D300 makes a long, laborious workflow possible to standardize. This technology removes the need for many wasteful steps, getting to results faster. HP enables biologists to shortcut the traditional serial dilution workflow.   [x]  Flexible plate map Create any plate map and dispense any dose in any well. Even randomize the plate with only one click! Traditional titration is typically restricted by the pipettor used. The HP D300's software is so simple to use that one can create any plate map desired in only minutes! Users can define any plate map in only minutes.   [x]  Drug-Drug Interaction Studies Drug-Drug Interaction Studies are becoming more and more important, yet because of the complexity of setting them up, many researchers are not running them as often as they might like. The HP D300, due to independent dosing of each compound, finally makes it possible to execute these experiments with ease. Set up Drug-Drug Interaction studies easily.   [x]  Digitial Dispensing HP D300 T8 cassettes dispense doses from 13pL up to 10µl directly into Bio-assay plates using HP's inkjet technology. These single use dispenseheads virtually eliminate cross-contamination. HP T8 cassettes

 

	Key benefits
	Effective direct titration Direct titration to assay plates More efficient experiment design Dispense any dose to any well Broad volume range from 13pl to 10μl CVs <8% for volumes greater than 100pl More secure titration curves as each volume is independently dispensed
	Cost savings Minimize drug titration times Increase productivity with minimized set-up time Preserve precious compounds with dead volumes <2μl Decrease solvent consumption Reduce consumables requirements using fewer plates and tips

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